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“If you don’t take the Wegovy pill just right, very little of the drug is actually absorbed,” Korner said
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Although the overall mortality, CV and renal benefits of this class of drugs are clinically significant, our cases emphasize the need to identify whether GLP-1RAs can cause renal dysfunction in some patients, especially in the setting of CKD, both through volume depletion from known gastrointestinal side effects and through intrinsic mechanisms such as AIN and diffuse podocytopathies such as MCD and FSGS
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